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Diversity Characteristics of Extracellular Vesicle RNA


BA Xiaoyun1, WANG Yiting2, DUAN Ruxia1, FANG Liaoqiong1,2*

(1College of Biotechnology, Southwest University, Chongqing 400716, China; 2National Engineering Research Center of Ultrasound Medicine, Chongqing 401121, China)
Abstract:

Extracellular vesicles are a new type of intercellular communicative medium that can carry proteins, nucleic acids, lipids and other inclusions. They can transmit biological informational molecules to adjacent and distant cells and regulate the normal physiological and pathological development of recipient cells. It plays an increasingly important role in tumorigenesis and development, diagnosis and treatment of diseases, and cellular molecular biology research. As an important regulator of gene expression, RNA is a kind of abundant inclusions in extracellular vesicles, and there are many kinds of extracellular vesicle RNAs, the levels of distribution and classification haven`t been established, which means that there will be a big challenge in this research. This article focuses on the diversity of extracellular vesicle RNA, and reviews the advances in extracellular vesicle RNA.


CSTR: 32200.14.cjcb.2019.11.0022