Home > Browse Issues > Vol.41 No.9
Regeneration of Skeletal Muscle
FU Xin1, LI Hu2, YANG Wenjun1, HAN Wanhong3, ZHANG Yong3*, HU Ping1,2*
(1State Key Laboratory of Cell Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China; 2Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing 100101, China; 3The State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and School of Basic Medicine, Peking Union Medical College, Beijing 100005, China)
Abstract:
Skeletal muscle, as the biggest organ in human body, plays key roles in breathing, metabolism, body temperature maintenance, exercises, and other vital movements. Exercises, illnesses, and traumas can all cause skeletal muscle injury. Skeletal muscle regeneration mediated by muscle stem cell which could selfrenew, proliferate, and differentiatee into mature myofibers, is able to repair muscle injury to various extents. The regeneration of skeletal muscle is regulated by complex molecular network and several cell types present in the microenvironment to achieve timely regeneration. Here we review the recent progress in this field.
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