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The Role and Research Progress of miR-146a in Head and Neck Tumors
Yuan Jie1,2, Wu Linrong2, Hu Yan1,2, Xu Jie1,2, Shen Zhisen1,2*
(1Ningbo University School of Medicine, Ningbo 315211, China; 2Li Huili Hospital Affiliated to Ningbo University, Ningbo 315040, China)
Abstract:
MicroRNA (miRNA) is a kind of RNA molecule which is widely expressed in eukaryotes. It has no function of compiling proteins and is a member of non-coding RNA. In recent years, more and more studies have proved that miRNA is involved in the regulation of tumor cell proliferation, apoptosis, tumor tissue vascular formation, tumor metastasis, immune escape and so on. miR-146a is one member of the miRNA family, and its research results in tumor tissues are increasing day by day. In this paper, the role and research progress of miR-146a in head and neck tumors are reviewed.
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