Functional Identification of Enhancer and Its Research Progress in Agricultural Animals
Xie Junhui1,2, Sun Yan1,2, Wang Sheng1,2, Tian Xiaohuan1,2, Cao Jianhua1,2*
Gene transcription in eukaryotes is regulated by various elements, of which enhancers are important cis-regulatory elements capable of greatly promoting gene transcription. The function of enhancers is closely related to specific function or phenotype of cells, tissues and individuals. The abnormality of enhancers often leads to alteration of traits and occurrence of diseases. Thus, studying the function of enhancers is of great biological significance for revealing the underlying molecule mechanism of phenotype which is crucial for agricultural animal science. In this article, characteristics, identical method, activity detection and progress in agricultural animal research of enhancers are reviewed in order to provide basis and reference for relevant research of enhancers.
CN
EN