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The Role of AGO in Non-coding RNA Function
Zhang Meiling, Chen Sijia, Zhong Zhaohua*
(Department of Microbiology, Harbin Medical University, Harbin 150081, China)
Abstract:
The argonaute (AGO) protein family is found in almost all species and is a highly conserved basic protein. AGO protein plays an important role in the whole life process of cells, and participates in various cellular processes such as mRNA degradation, gene silencing, and protein translation. Understanding the mechanism of noncoding RNA genes is helpful to discover new regulators of organogenesis, embryonic development and growth, to understand the pathogenesis of human diseases, and to provide theoretical basis for the development of new treatments for various diseases. This review focuses on the biological role of AGO in non-coding RNA.
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