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Research Advances of Fibroblast in Diabetic Wound Healing


Wang Xiaoyu, Zhang Yujie, Qu Chunan, Tang Shengjian, Li Yuli*

(Institute of Reconstructive Plastic Surgery, Weifang Medical University, Weifang 261053, China)
Abstract:

Diabetic skin is vulnerable. The delayed healing results from its complicated abnormal pathophysiology process. The wound reduces the patient’s quality of life and makes it becomes a difficult and hot pressing. Fibroblasts are one of the important components of skin tissue, the key and foundation to the wound healing as well. In recent years, the study of the effect of diabetes on fibroblasts and its changes is developing rapidly. It is found that the change of the diabetic fibroblasts in the wounds painless plays an important role. This paper reviewed the effect of diabetes on FB and the changes of FB in wound healing in order to understand its mechanism.



CSTR: 32200.14.cjcb.2019.04.0021