Tissue Engineering of Vital Organs

Tissue and organ loss or dysfunction is one of the major hazards threatening human health, and also the most important cause of human disease and death. How to fundamentally solve tissue and organ defects or dysfunction has become an international frontier subject to be actively explored by the scientific community, especially in the field of life science. The ultimate goal of tissue engineering is that engineered products can be used to replace the tissues/organs with irreversible damage and function degradation, which enables more patients to receive timely treatment and fundamentally addresses vital organdiseases to improve the health level and quality of life of human beings. After more than 20 years of unremitting efforts, tissue engineering research has made great progress. Tissue engineering research on important vital organs has become a new focus in the field of tissue engineering. Breakthroughs have been made in tissue engineering of the heart, liver, kidney, pancreas and other vital organs. This article reviewed the latest progress and the relevant industrialization situation of important vital organ tissue engineering researches at home and abroad, including directional control stem cell differentiation, functional bionic scaffold materials preparation, important organ in vitro building and application, and organ precise design and manufacture based on rapid prototyping and micro manufacturing technology, etc. This article could provide certain reference for important vital organ tissue engineering research and industrialization development.

CSTR: 32200.14.cjcb.2019.04.0005