Home > Browse Issues > Vol.41 No.3
Advances in Organoid Technology
Yang Tao#, Sun Yu#, Chen Jiajia, Liu Qinggui, Wang Minjun, Hu Yiping*, Chen Fei*
Department of Cell Biology, Naval Military Medical University, Shanghai 200433, China
Abstract: The organoids are three-dimensional cell complexes with a certain spatial structure formed by in vitro cultured descendant cells differentiated from organ-specific stem cells or progenitors. Organoids have certain structural and functional properties similar to those of the source organs. They are capable of stable amplification in 3D (three-dimensional) culture systems. At present， organoids have shown broad application in basic biological research， construction of disease models， tumor research， tissue regeneration and repair， gene therapy， and drug screening. This review will briefly introduce the development of organoid culture systems and their applications in life science research.
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