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Basic Properties of Actin Filaments and Nuclear Actin
Wu Congying*
Institute of Systems Biomedicine, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, China
Abstract: Microfilaments are seen in almost all the eukaryotic cells. Actin， the building block of the microfilaments， generates and transduces cellular forces and promotes cell motility when working in concert with the motor protein myosin. Although it has been noticed long ago that actin monomers existed in the nucleus， the role and dynamics of the polymerized actin filaments have been under debate. Here， we review the general properties and the nucleation process of the microfilaments. We also discuss recent advances in nuclear actin.
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