“Liquid-Liquid” Phase Separation of Biological Macromolecules: Current Situation and Prospects
Gao Yifei*, Li Pilong*
The “liquid-liquid” phase separation of biological macromolecules is a new concept that has rapidly developed in the field of life sciences in recent years. The concept of phase separation provides a new perspective and research tool for us to deeply understand the organization mode and function regulation of intracellular biomacromolecules, and thus quickly becomes the research frontier in the life science field. But there are still many unsolved mysteries surrounding the biophysical properties of biomacromolecular phase separation and their role in cells. In this paper, recent studies on the phase separation of biomacromolecules have been reviewed, and their functions in the cell and future development trends have been discussed and prospected.
CN
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