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The Progress of Methods Studying Protein Trafficking


Wang Zhe1, Xu Pingyong1,2*  

1Key Laboratory of RNA Biology, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China; 2College of Life Sciences, University of Chinese Academy of Sciences, Beijing 100101, China
Abstract:

Special localization and polarization distribution of protein which are achieved by trafficking after translation in ribosome is essential to maintain normal function of proteins. The emergence of novel labeling techniques and imaging strategies can directly be used to observe the transport process of proteins in cells and study molecular mechanism of protein trafficking. This review focuses on techniques and methodological strategies for studying protein trafficking.


CSTR: 32200.14.cjcb.2019.01.0003