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Monozygotic Twins and T Cell Repertoire
Su Danhua, Dong Xiaoheng, Ma Long, Yao Xinsheng*
Special Key Laboratory of Gene Detection & Therapy of Guizhou Province, Department of Immunology, Zunyi Medical University, Zunyi 563000, China
Abstract: In recent years， high-throughput sequencing has been applied to study T cell receptor (TCR) in domestic and foreign. As the executor of the adaptive immune response， the T cell receptor (TCR) on the surface of T cell is the key to the adaptive immune response. At present， there are not enough studies about TCR on the background of monozygotic twins. In order to better understand the characteristic of TCR receptor repertoire of healthy individual and patient suffering from immune-related disease under the same genetic background， this article will summarize the characteristic of TCR receptor repertoire of healthy monozygotic twins and the characteristic of TCR receptor repertoire of monozygotic twins suffering from immune-related disease.
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