Gonadotropin-Releasing Hormone Immunomodulatory Function

Abstract: With the deepening of the study of the interaction between the nervous system and the immune system， the influence of neurohormones in the immune system is increasingly being focused. Gonadotropinreleasing hormone is synthesized by the hypothalamus. Both gonadotropin-releasing hormone and its receptors are found in immune cells， suggesting that gonadotropin-releasing hormone has an autocrine or paracrine action in the immune system. It has immunomodulatory effects on immune response， cell proliferation and activity， immune medium release and cell function， at the same time it has a certain influence on autoimmune diseases. Gonadotropin-releasing hormone may be an important component of the immune system regulation and have an effect on the regulation of immune-mediated diseases， it plays an important role in constructing the network of three systems of neural， immune and endocrine.

CSTR: 32200.14.cjcb.2018.09.0016