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Sepsis and Neutrophil Abnormal Migration
Zhang Cunling, Liu Fei, Xu Yuanfu*
State Key Laboratory of Experimental Hematology, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China
Abstract: Sepsis is one of the top leading causes of death in intense care unit patients， which is becoming more prevalent in recent years. It is well known that the pathological mechanism under sepsis is the impaired immunological function， and neutrophils are the important immune cells in the body. Recently， more and more studies showed that the dysfunctional neutrophils might affect prognosis in sepsis patients. This review focus on exploring abnormal migration capacity of neutrophils in sepsis.
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