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The Correlativity among Antiphospholipid Antibodies, Tumors and Thrombosis


Yan Songxin1, Pan Yi2, Wang Hongmei2*
1Medical College of Nanchang University,Nanchang 330006, China; 2Basic Medical College of Nanchang University, Nanchang 330006, China
Abstract: Antiphospholipid antibodies (aPL), as aseries of autoantibodies, can react with numerous phospholipids substances in the human body. Despite causing autoimmune diseases, aPL can also cause thrombosis and other pathological reactions. It was found that the detection rate of aPL is higher in cancer patients than the general population. Moreover, tumor is often accompanied by thrombosis and can further cause related clinical symptoms. There are certain correlativity and interactions among aPL, tumors and thrombosis, nevertheless, the exact relationship remains obscure. This review aims to summarize and clarify the latest progressesin this field by focusing on the relevant studies in recent years. We think this review will provide some novel insights and directions for further researches.
    


CSTR: 32200.14.cjcb.2018.01.0020