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Advances in Cell Metabolomics Based on Mass Spectrometry


Wang Siyuan, Zhao Xingyang, Xu Weiwei, Liu Huiwen*
Department of Histology and Embryology, Harbin Medical University, Harbin 150081, China
Abstract: Cell metabolomics is an emerging field that addresses fundamental biological questions and allows observation of metabolic phenomena in cells. Cellular metabolite concentrations closely reflect the phenotype of an organism, tissue, or cell. With the development of metabolomics, thetechnology of metabolomics which is based on mass spectrometry can be applied to study cell metabolites. And it has high sensitivity, good resolution, the capability for multi-species detection and molecular structure identification, which is significant in the research of cell biology. In this review, combining with the current technology of the metabolomics, the study significance of cell metabolites and the applications of cell metabolomics based on mass spectrometry are reviewed.


CSTR: 32200.14.cjcb.2017.08.0019