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Progress of TLRs in Regulating Neutrophil Immune Function Against Bacterial Infection
Lu Shanshan1, Chen Yiguo2, Min Weiping1*
1Department of Pharmacy, Nanchang University Medical College, Nanchang 330006, China; 2Clinical Laboratory, Jiangxi Provincial People’s Hospital, Nanchang 330006, China
Abstract: When the pathogenic microorganisms invade the human body， the body will produce inflammation and recruit more immune cells in the inflammatory site to resist the invasion of microorganisms. Toll-like receptors (TLRs)， as the main receptors of the pathogens， play an important role in innate immunity. And neutrophil is the main effector cell in the nonspecific reaction and can be adjusted the intensity of bacteria inflammatory reaction. Therefore， in the inflammatory response of bacterial infection， neutrophils and Toll-like receptors are expected to find effective immunotherapy against bacterial infection.
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