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RNase Activity and Regulation of the UL41 Gene Encoding Protein of HSV-1
He Tianqiong, Cheng Anchun*, Wang Mingshu*
Avian Diseases Research Center, College of Veterinary Medicine, Key Laboratory of Animal Diseases and Human Health of Sichuan Province, Institute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China
Abstract: The tegument protein encoded by UL41 gene of herpes simplex virus type-1 (HSV-1) acts as an mRNA-specific RNase activity， which involved in host immune evasion and associated with other proteins to regulate its RNase activity. This paper reviewed the RNase activity and regulation mechanism of this protein， and provided a reference for further study of this gene.
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