Home > Browse Issues > Vol.38 No.12
Transcription Factors SCX and MKX Research Progress in Tendon Development and Differentiation
Wu Zhen1, Zhang Ziwang2, Wang Xiaoai3, Zheng Liling2, Wu Fang3*
1Tongde Hospital of Zhejiang Province, Hangzhou 310012, China;
2Zhejiang University School of Medicine,Hangzhou 310058, China;
3The Children’s Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China
2Zhejiang University School of Medicine,Hangzhou 310058, China;
3The Children’s Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China
Abstract: Tendon injury is one of common clinical diseases. It is very easily to do harm to tendon function due to the adhesion. Thus， the effective improvement and promotion of healing and recovering of tendon function become main problems to be solved. In order to find the methods to solve the problem at the source， many scholars on tendon development mechanism carried out a large amount of research， finding that the key transcription factors of tendon development and differentiation are SCX (Scleraxis) and MKX (Mohawk). In order to have a better understanding about the tendon development mechanism， this paper mainly introduce the discovery of transcription factor SCX and MKX along with their function， signaling pathways and some other aspects involved in the tendon.
CN
EN