Home > Browse Issues > Vol.38 No.11
Effects of G Protein-Coupled Receptor Oligomerization on Receptor Functions
Guo Jingming, Liu Ying, An Shu, Guo Xiaoxi, Xu Tianrui*, Yang Yang*
Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, China
Abstract: G protein-coupled receptor (GPCR) represents the largest family of surface membrane receptors involved in photosensitizing， osphresis and behavior regulation， as well as a variety of physiological processes such as the regulations of autonomic nervous and immune system. GPCR plays an important role in signal recognition and transduction in form of oligomers. This review will sum up the research progress of GPCR oligomerization，and the effects of oligomerization on receptor structure， internalization， signal transduction and pharmacological physiology.
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