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Progressin the Study of Antiretroviral Therapy Related Cardiovascular Diseases in AIDS Patients
Song Lin, Sun Yi, Yu Luyang*
College of Life Sciences, Research Center for Air Pollution and Health, Zhejiang University, Hangzhou 310058, China
Abstract: The successful roll-out of antiretroviral therapy (ART) makes HIV infection into a manageable clinical entity. However， more and more clinical evidences define an elevated risk of developing cardiovascular disease (CVD) among HIV-positive patients who are with medical care. Beside immunological defect and metabolic disorder， adverse effects of antiretroviral therapy have become of particular concern within factors that may potentially contribute to HIV-related CVD. Currently， the effects of ART on cardiovascular disease are mainly linked with two kinds of backbone drugs， nucleoside reverse transcriptase inhibitors (NRTIs) and protease inhibitors (PIs). The aim of this review is to introduce the research progresses of ART related cardiovascular diseases in AIDS patients.
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