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Origin， Biogenesis and Mechanism of Plant and Animal microRNA
Ma Zhiming, Cao Jiashu*
Laboratory of Cell & Molecular Biology, Institute of Vegetable Science, Zhejiang University, Hangzhou 310058, China
Abstract: microRNA (miRNA) is a kind of 20-23 nt endogenous non-coding small RNA in eukaryotes， which is widely existed in animals and plants. Although animal and plant miRNA participate in a wide range of growth and development processes both through negatively regulating their target genes at post-transcriptional levels， their origin and biogenesis pathways are different， and their working mechanisms for target gene regulation are also diverse. In this review， similarities and differences of the origin， biogenesis and mechanism between plant and animal miRNAs were summarized and discussed to provide theoretical basis for deeply studying the miRNAs in plants and animals.
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