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Clinical Research Progress in Stem Cell-based Therapies for Age-related Macular Degeneration


Zhu He1,2, Wang Lei2, Wu Jun2, Hao Jie2*
1Hubei Provincial Key Laboratory for Protection and Application of Special Plants in Wuling Area of China,South-Central University for Nationalities, Wuhan 430074, China;
2State Key Laboratory of Stem Cell and Reproductive Biology,Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China
Abstract: Age-related macular degeneration (AMD) is one of the main causes of blindness in people over 60 years old, but to date there’s no effective treatment. Stem cells hold characteristics of self-renewal and differentiate into a variety of tissue cells. This poses a potential hope for the treatment of these incurable diseases. Today,there have been a lot of clinical trials using stem cell related products for the treatment of AMD at home and abroad,and encouraging results have been showed. However, there are still many problems should be solved for the real application of stem cells to treat AMD. Herein, stem cells transplantation method, cells types and existing problems will be reviewed.


CSTR: 32200.14.cjcb.2016.06.0015