Home > Browse Issues > Vol.37 No.12
Progress in the Regulation of Adipocyte Differentiation
Gao Yang, Wei Zhuying, Bai Chunling, Li Guangpeng*
National Center for Animal Transgenic Biotechnology of Inner Mongolia University, Hohhot 010010, China
Abstract: On the morphology， animal fat can be divided into white fat， brown fat and beige fat. Marrowderived and adipose-derived mesenchymal stem cells flowed into all kinds of tissues and organs through blood circulation， after formed adipose progenitor by cell proliferation， and differentiate into fat cells and mature fat cells. Under physiological conditions， white fat and brown fat can be converted each other， they are dynamic conversion process. If the balance between the two adipose is broken， a variety of diseases would be caused， such as obesity， type II diabetes， high blood lipids， fatty liver， cardiovascular disease and breast cancer. Beige fat is an intermediate in the process of white and brown fat conversion. Conversion between different types of fats is affected by several factors and their regulation mechanism， this article will be reviewed to describe the fat differentiation and its regulation mechanism.
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