Home > Browse Issues > Vol.37 No.9
Long Noncoding RNA and Cervical Cancer
Li Shujuan1*, Tang Yitong2
1Xi’an Innovation College of Yan’an University, Xi’an 710100, China;
2Hubei University of Arts and Sciences, Xiangyang 441053, China
2Hubei University of Arts and Sciences, Xiangyang 441053, China
Abstract: Long noncoding RNAs (lncRNAs) are greater than 200 nucleotides in length with non-protein coding transcripts. LncRNAs play an important role in human carcinogenesis. They regulate the expression of genes at the epigenetic， transcriptional and post-transcriptional levels and are associated with the occurrence，development， invasion， metastasis and prognosis of tumors. Recent studies show that lncRNAs have been expressed abnormally in cervical cancer， playing oncogenic or tumor suppressive activity. They may become new targets for molecular diagnosis and gene therapy of cervical cancer. In this paper， the latest research and progress of lncRNA in cervical cancer are reviewed.
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