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Advances in Mesenchymal Stem Cells in the Regulation of Inflammation
He Xiao, Huang Hong, Xu Xiang*
State Key Laboratory of Trauma, Burns and Combined Injury, Institute of Surgery Research, Daping Hospital,Third Military Medical University, Chongqing 400042, China
Abstract: Mesenchymal stem cells are a group of multi-potent adult stem cells. Beside their active effect in tissue regeneration and wound healing， they also show good immune regulatory effect. By regulating proliferation， differentiation， and functional status of immune cells， they can regulate secretion of inflammatory cytokines， showing great potential in inflammation-related diseases. This review aims to briefly summarize the advances for their immunoregulation ability. The application of the mesenchymal stem cells in preclinical trials is also described.
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