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The Development of Three-Dimensional Cell Culture Technology and Its Application in Stem Cells and Tumor Cells


Zhao Diandian, Hou Lingling*, Zhang Jingsi, Hu Honggang, Yan Qiong
College of Life Science and Bioengineering, School of Science, Beijing Jiaotong University, Beijing 100044, China
Abstract: Three-dimensional cell culture technique is a kind of simple and effective culture system
    which is developed on the basis of the two-dimensional cell culture and in vivo animal model. Three-dimensional
    cell culture can better mimic the in vivo cell environment and provide a new research tool for the relevant fields.
    At present, three-dimensional cell culture technique is used in many areas, including tissue engineering, tumor
    treatment, regenerative medicine and stem cell biology, etc. Here, we review recent research progress in threedimensional
    cell culture technique and its application in stem cells and tumor cells.


CSTR: 32200.14.cjcb.2015.08.0013