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Transcription Factors GATA and Hematological System Diseases


Wei-Wei Liao, Xiu-Jing Ye*
The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, China
Abstract: Transcription factors GATA are important regulating factors of hematopoietic system. Recently researchers discovered the GATA transcription factors are not only associated with the regulation of hematopoietic system, its mutation and aberrant expression are also linking to the proceed and development of hematological system diseases. This article mainly reviewed the relationship between the mutation and aberrant expression of GATA and hematologic system diseases.
    


CSTR: 32200.14.cjcb.2007.04.0008