Home > Browse Issues > Vol.37 No.4
Microglia and Related Neurodegenerative Diseases
Wu Haige*, Liu Yuqing, Yao Ziang
College of Life Science and Technology, Dalian University, Key Laboratory of
Glycolipid Metabolism of Liaoning Province, Dalian 116622, China
Abstract: Microglia (MG) are resident immune cells of the central nervous system (CNS) and widely distribute in the central nervous system， which play an important role in immune surveillance. Researches have shown that microglia have a close relationship with neurodegenerative diseases， such as Alzheimer’s disease (AD)， Parkinson’s disease (PD)， Amyotrophic lateral sclerosis (ALS) and so forth. Hence， clarifying the pathogenesis of microglia has an important theoretical significance and practical value for clinical prevention and treatment of related neurological diseases. Nowadays， the microglial research contents have not been classified systematically， although the researches on its functions and regulation mechanisms are plentiful. Here， the recent research progress on microglial pathogenesis and some correlative neurodegenerative diseases are summarized.
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