Home > Browse Issues > Vol.29 No.4
Brain Tumor Stem Cells
Rui Niu, Hong Liao, Ding-Ding Chen, Wen-Hui Huang, Lu-Yong Zhang*
Neurobiology Lab, New Drug Screening Center, China Pharmaceutical University, Nanjing 210038, China
Abstract: Brain tumors， especially malignant glioblastoma and melluloblastoma， are often lethal just because of their proliferation and recurrence very quickly. Therefore， it will be difficult problem be solved urgently that exploring of the arising of brain tumor and reasons of brain tumor recur in tumor researching and clinical therapy. Recently， the conception of tumor stem cells and the isolation and identification of brain tumor stem cells provide a new approach to explore the puzzle about the brain tumors. In this review， we will discuss the proposing of tumor stem cell theory and introduce some progress about brain tumor stem cells (including unlimited proliferation， self-renewal， multipotent differentiation， genesis， and so on). All these researching work will provide one kind of new direction for brain tumor clinical implication such as diagnosis， therapy and development of drug for targeting the tumor stem cells.
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