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The Effects of Fatty Acids in Oocyte on Oocyte Maturation and Development
Jia Zhenwei*, Zhang Yongchun, Zhang Xianhua, Gao Shuxin
Institute of Yellow Cattle Genetics-Breeding and Reproduction, College of Animal Science and Technology,Inner Mongolia University for the Nationalities, Tongliao 028043, China
Abstract: It is widely believed that fatty acids, as nutrient substance with important biology function, have a positive effect on lipid metabolism, gene expression and function of cell membrane in animals. Moreover, a growing body of evidences indicates that oocyte quality can be affected by fatty acids concentration, type and ratios in the diet. To predict oocyte quality using metabonomics methods has so far become a research hot spot in reproductive biology, which focuses primarily on glucose and amino acid metabolism. Animal oocytes contain large amounts of endogenous fatty acids, but little is known about its metabolism in oocytes. Furthermore, fatty acids also act as a signal molecular for the regulation of gene expression, and are a necessary component of biological membranes. Therefore, this review highlights the source and categories of fatty acids, their physiological action and effect on oocyte maturation and development, which will provide the basic for promoting oocyte maturation and development, thereby improve animal fertility by regulating the composition and application of fatty acids in the future.