Advances in Relationship between MicroRNA and Development of T Lymphocyte

Jia Zhekun^1,2, He Yulong^1,2, Li Min^1,2*, Hao Xiujing^1,2

¹Key Laboratory of Ministry of Education for Conservation and Utilization of Special Biological Resources of Western China,Yinchuan 750021; ²Ningxia University School of Life Science, Yinchuan 750021, China

Abstract: MicroRNA (miRNA) is a class of small non-coding RNA molecules， 21~25 nucleotides long. miRNA can target the certain mRNA and modulate the gene expression at the post-transcriptional level. They play important roles in diverse biological processes including immune. Recent studies showed that miRNA could regulate the development and activation of immunocytes by targeting the critical signals of the pathways. In this review， we summarized some recent research progresses of miRNA involved in the development， differentiation and function of T cells.

CSTR: 32200.14.cjcb.2015.01.0013