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Progress in Profilin


Jiang-Tao Xu, Yao-Zhou Zhang*
Institute of Biochemistry, College of Life Science, Zhejiang Sci-Tech University, Hangzhou 310018, China
Abstract: Profilins are a kind of low molecular weight actin binding protein, which are ubiquitous in eukaryotes. There are more and more experiments proving that profilins not only bind to actin but function as a hub in the network of molecular interactions, and the importance of which has just been noticed in recent years. We review the recent researches on profilin gene family, its role in signal transduction, ligands binding, and its modification during regulation. And we also discuss the recent hypothesis and propound prospects.


CSTR: 32200.14.cjcb.2007.03.0005