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Inhibitory Effects of Tea Catechins on Tumor Angiogenesis


Yu-Yan Zhang, Rong-Sheng Shen*
Institute of Tea Sciences, Zhejiang University, Hangzhou 310029,China
Abstract: The progress showed in the recent investigation of antiangiogenic mechanisms of catechins was reviewed in this paper. The mechanisms of angiogenic activity were discussed from the following three aspects: inhibition of the vascular endothelial cell proliferation, inhibition of cell adhesion molecule expression and suppression of basement membrance degradation, in the meantime, the investigational problems in existence and the development of catechins in the future were tentatively discussed as well.


CSTR: 32200.14.cjcb.2005.03.0007