The Repairing of Sinonovacula constricta on Mice Irradiated by ⁶⁰Co γ-Rays

Abstract: We studied the repairing effect of Sinonovacula constricta on genetic injury of ICR male mice induced by 60Co γ-rays. Mice with 6-7 week age were irrigated respectively by 100 mg/(kg⋅d)， 200 mg/(kg⋅d)， and 400 mg/(kg⋅d) Sinonovacula constricta for 10 d. PCE micronucleus test and sperm deformity test were used to measure the index of spleens and chest glands， the number of karyote and the frequency of PCE micronucleus， and the frequency of sperm deformity. The result showed that the 3 different concentrations of Sinonovacula constricta made increase significantly the index of spleens and chest glands， the number of karyote that had been decreased by ⁶⁰Co γ-rays (P<0.001). The three different concentrations of Sinonovacula constricta made decrease significantly the frequency of PCE micronucleus and sperm deformity decreased by ⁶⁰Co γ-rays (P<0.001). The conclusion is that the test concentrations of Sinonovacula constricta have obvious repairing effect on the genetic injury of male mice radiated by ⁶⁰Co γ-rays.

CSTR: 32200.14.cjcb.2009.04.0020