Home > Browse Issues > Vol.32 No.5
Research Progress of Induced Pluripotent Stem Cells
Ri-Na Sa1, Xi-He Li1,2, Rong-Feng Li1*
1Key Laboratory of Ministry of Education of China for Mammal Reproductive Biology and Biotechnology, Inner MongoliaUniversity, Hohhot 010021, China; 2Inner Mongolia Mengniu Reproductive Biotechnology CO.,LTD.,Shengle Economic Distric
Abstract: The recent success on induced pluripotent stem cells (iPSC， iPS Cells) is a significant landmark for Stem Cells research， which has been a hot topic in life science field. Japanese and American scientists successfully established mouse and human iPS cell lines in 2006 and 2007 respectively and only three years later， iPS cells research has been developed at tremendous rapid and numerous relative improvements and breakthroughs have been achieved in both of basic and application fields. iPS cells ranked number 1 of top 10 science stories in Nature Science times (2007) and Science (2008). This review summarizes the background of iPS cells research， the different strategies used to generate iPS cells and their developments， application status on mammals and the prospects and problems of current iPS cells techniques. This review might be helpful for related scientists to further investigate iPS cells.
CN
EN