Home > Browse Issues > Vol.36 No.9
Research Advances of Gene Related to Laryngeal Carcinoma
Wang Beilei1, Xu Lihong1, Yuan Hui2, Lin Zhihong2*2*
1Department of Biochemistry, School of Medicine, Zhejiang University, Hangzhou 310058, China; 2Department of Otolaryngology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China
Abstract: Laryngeal carcinoma is one of the most common malignant neoplasms of the head and neck. The major pathological type of laryngeal cancers is squamous cell carcinoma. The occurrence and development of laryngeal cancer is more than one gene involved， multi-stage and multi-level complex process. Recent studies show that laryngeal carcinoma is related with EGFR， COX-2， Survivin， VEGF， STAT3， p16， p53 and Cyclin D1. Through in-depth study of these genes， gene therapy provides new ways for laryngeal cancer clinical treatment and prevention， and has an extremely important significance to overcome the human larynx.
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