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Recent Progress of Porcine Pluripotent Stem Cells


Li Xia, Li Yunsheng, Zhang Yunhai*
Anhui Provincial Laboratory for Local Livestock and Poultry Genetic Resource Conservation and Breeding,College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China
Abstract: Pluripotent stem cells, such as embryonic stem cells, induced pluripotent stem cells and adult stem cells, are unique cells with great value. Pigs are considered as a kind of more ideal biomedical model in human xenotransplantation and regenerative medicine, bearing similar properties with human in genetic, metabolism, physiology, biochemistry and gene sequence. However, limited information on the sorting, derivation, characterization and mechanisms of porcine pluripotent stem cells impairs their application. Herein, we briefly reviewed the latest progresses about the derivation, current status, interrelationships and future perspectives of porcine pluripotent stem cells, in order to providing a useful reference for researchers’ working in this filed.


CSTR: 32200.14.cjcb.2014.02.0016