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Research Progress on Osteogenic Differentiation of Amniotic Fluid-derived Stem Cells
Si Jiawen1, Shen Guofang1*, Guo Lihe2*
1Department of Oral and Maxillofacial Surgery, Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine,Shanghai 200011, China; 2Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences
Abstract: In 2007， de Coppi et al reported the isolation of a stem-cell subpopulation with multi-differentiation potential from amniotic fluids in the journal of Nature Biotechnology， which prove that amniotic fluids may become a promising source of stem cells， in addition to specimens for prenatal diagnosis. Amniotic fluid-derived stem cell， a special type of stem cells， has been shown to possess unique biological characteristics and a comprehensive multi-differentiation potential. With further research， amniotic fluid-derived stem cells gradually show the potential value of research and application in osteogenic tissue regeneration. So it is necessary to review the research progress on characteristics and osteogenic differentiation of amniotic fluid-derived stem cells， which may provide references for other relevant study.
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