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Progress of Study on Hedgehog Signaling Pathway
Qi Xiaolong1, Wang Yujiong1, Wu Geng2*
1School of Life Sciences, Ningxia University, Yinchuan 750021, China; 2School of Life Sciences and Biotechnology,Shanghai Jiao Tong University, Shanghai 200240, China
Abstract: Hedgehog (Hh) signaling pathway is one of the hottest pathways in present research. It is a conserved signalling system essential to the development of vertebrates and invertebrates. In addition， it is showed that the aberrant Hedgehog signaling is relative to tumorigenesis. To provide useful information for the study of relative fields， here we summary the recent advance on how are the production， propagation， reception， and transduction of the Hh signal controlled through the pathway components and the relationship between cancers and this pathway.
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