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Epigenetics and Its Correlation with Disease
Li Wen, Bian Yuhong, Chu Xiaoqian*
1Tianjin University of Traditional Chinese Medicine, Tianjing 300193, China; 2Tianjin International Jiont Academy of Biotechnology & Medicine, Tianjing 300457, China
Abstract: Epigenetics involves in the changes of gene expression and function and generateion of hereditable
phenotype without alteration of DNA sequences. The regulation mechnisms of epigenetics include DNA
methylation， histone modification， chromatin remodeling， non-coding RNA. These epigenetics changes are bound
up with many kinds of diseases. This paper reviews on the correlation between epigenetics and diseases.
phenotype without alteration of DNA sequences. The regulation mechnisms of epigenetics include DNA
methylation， histone modification， chromatin remodeling， non-coding RNA. These epigenetics changes are bound
up with many kinds of diseases. This paper reviews on the correlation between epigenetics and diseases.
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