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Integrated Intracellular Signal Pathways Response Induced by Tributyltin


Liu Huigang1, Xu Lihong2*
1School of Medicine, Three Gorges University, Yichang 443002, China; 2Department of Biochemistry, School of Medicine, Zhejiang University, Hangzhou 310058, China
Abstract: The intracellular response induced by tributyltin (TBT), a kind of marine pollutant, is a very
    complex integrated network-like intracellular response. All the cytokines that participate the intracellular response
    assembled an “integrated circuit”, in which several both relatively independent and mutually related react modules
    were formed. The present review focuses on the integrated network-like intracellular response induced by TBT. The
    purpose of this review is to provide reference for comprehensive evaluation of the harm of environmental pollutants.


CSTR: 32200.14.cjcb.2013.01.0011