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Progress of Interactions between Mycobacterium tuberculosis and Macrophages
Liu Yunxia, Zhang Wanjiang*
Shihezi University School of Medicine, The Key Laboratory of Ministry of Education of Xinjiang Endemic and Ethnic Disease,Shihezi 83200, China
Abstract: Macrophages are the main host of Mycobacterium tuberculosis, a kind of typical intracellular pathogen bacteria. Macrophages have a powerful phagocytosis, which plays an important role in both innate immunity and adaptive immunity and can effectively protect host from Mycobacterium tuberculosis infection. In the long-term interaction process with host macrophages, Mycobacterium tuberculosis gradually formed a variety of effective strategies to avoid killing to survive and proliferate in the host. This article from macrophages resistance to Mycobacterium tuberculosis infection and Mycobacterium tuberculosis evading macrophages killing reviewes domestic and international research.