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Biological Function of Chemokines and Chemokine Receptors from Mesenchymal Stem Cells
Ying Wang, Ning-Li Li*
Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine Shanghai 200025, China
Abstract: Mesenchymal stem cells (MSCs) are stem cells that exist in bone marrow interstitial or other matrix which can express CD34 and CD133. Bone-marrow derived MSCs not only have the ability of haematogenesis， differentiation into osteoblasts， adipocytes and chondrocytes， recent study reveals that the chemokines they secreted and MSCs-related receptors also play an important role in signal conduction， homeostasis， injury repair and immunity regulation.
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