Home > Browse Issues > Vol.33 No.4
Impacting Factors for Induced Pluripotent Stem Cells
Li-Na Tang1,2, Yang Zhang1, Guang-Qi Song1, Wei Shi2*, Zi-Yi Li1*
1Jilin Province Key Laboratory of Animal Embryo Engineering, College of Animal Science and Veterinary Medicine, Jilin University Changchun 130062, China; 2Key Laboratory for Molecular Enzymology and Engineering, the Ministry of Educa
Abstract: Direct reprogramming of somatic cells to induced pluripotent stem cells (iPSCs) provides an invaluable resource for regenerative medicine， enabling the generation of patient-specific cells of any lineage without the use of embryonic material. We compared the currently reported protocols， identified the essential steps common to these methods， and summarized several factors that affect iPS cells reprogramming process， with an emphasis on standardization of certain parameters for accurate comparison between independent experiments.
CN
EN