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The Effect of Notch Signal Pathway on Stem Cell Differentiation
Ying-Wang, Hui-Cheng Xu*
Department of Obstetrics and Gynecology, First Affiliated Hospital, Third Military Medical University, Chongqing 400038, China
Abstract: The proliferation and differentiation of stem cells are regulated by a variety of signaling pathways (internal or external， and local or distance)， and the communications between cells play an important role in this process. Notch pathway is just one of the important molecules which regulate cell differentiation via the communications between adjacent cells. Through great quantity of research， the important regulatory role of activating this pathway in the process of stem cell differentiation is confirmed. All progresses concerning this researching will be reviewed in the present paper.
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