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Research Progress for Searching Tumor Metastasis-related Protein Markers by SELDI-TOF-MS Technology


Wei Liu1, Shen-Hua Xu2, Wei-Min Mao2*
1Wenzhou Medical College, Department of Oncology, Wenzhou 325000, China; 2Zhejiang Cancer Hospital, Zhejiang Cancer Research Institute, Hangzhou 310022, China
Abstract: Due to the advantages of SELDI-TOF-MS technology including simpleness, fastness, high sensitivity and good repeatability, this technology is widely applied in the tumor-related research and provides effective methods of searching tumor-associated protein markers, which, in particular, gets more and more attention because of the roles it played in searching for tumor metastasis-related protein markers. This paper presents and summaries in detail the relative research of the SELDI-TOF-MS technique in search of the tumor metastasisassociated protein markers.


CSTR: 32200.14.cjcb.2011.01.0014