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Focal Adhesion Kinase: Implications with Oncogenesis， Tumor Development and Prognosis
Yan-Li Yang, Peng-Ge Li, Yu-Ting Ge, Tian-Le Yin, Ying-Chun Hou*
College of Life Science, Shaanxi Normal University, Xi，an 710062, China
Abstract: It is reported that focal adhesion kinase (FAK) is excessively expressed in many tumors， which is associated with cell invasion， proliferation， cell motility， apoptosis， oncogenesis， and tumor development. It is also reported that FAK may act as a prognosis factor for tumor development， and serve as a potential new target for cancer therapy. In this paper， the advances described as above are reviewed and summarized， and the feasibility of FAK as a tumor marker for tumor diagnosis and prognosis was estimated.
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