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Progress in Paneth Cell α-defensin
Yu-Rong Yang, Xi-Lan Jiao, Hong-De Liang*
College of Animal and Veterinry Engineering, Henan Agricultural University, Zhengzhou 450002, China
Abstract: Paneth cell α-defensin plays a pivotal role in maintaining intestinal homeostasis and innate immunity of animals. The change of Paneth cell had related with intestine dysfunction. Recent studies provide evidence that Paneth cell α-defensin expression disorder may be a key pathogenic factor in inflammatory bowel disease. This article reviewed the distribution， morphology， biology characteristics of Paneth cell， biosynthesis and function of Paneth cell α-defensin.
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