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Application of DSC in Erythrocyte


Ji Yuan, Xin-Li Zhou*, Hai-Song Wang
Institute of Biothermal Science, Shanghai University of Science and Technology, Shanghai 200093, China
Abstract: Differential scanning calorimetry (DSC) measures the difference of heat flow rate between sample and reference sample under controlled temperature program. Thermal parameters (e.g., enthalpy, heat capacity and phase transition temperature) derived from thermogram can be used to access the structual changes in cell. The combination of thermoanalytical technique and structural analysis contributes significantly to interpreting physiological changes in cells. This paper introduced theoretical evaluation on optimal cooling rate and membrane damage, which shed lights on the application of DSC in erythrocyte.


CSTR: 32200.14.cjcb.2010.05.0021